Prof Clarke is a medical oncologist, pharmacologist and translational researcher with major clinical and research interests in gastrointestinal and thoracic cancers and pharmacology. He is a medical oncologist at the Northern Cancer Institute and Royal North Shore Hospital, Director of Cancer Services at Northern Sydney Local Health District and Professor of Medicine at the University of Sydney.
Prof Clarke completed his medical degree at the University of Sydney in 1983 and an FRACP in Medical Oncology at Royal North Shore Hospital in 1990. He then completed a PhD at the University of London at the Institute of Cancer Research / Royal Marsden Cancer Hospital. Prof Clarke returned from the UK in 1994 and has worked at Westmead, Nepean, Concord and Royal Prince Alfred Hospitals prior to returning to Royal North Shore Hospital in 2010. He obtained an MD from the University of Sydney in 2011.
Prof Clarke was awarded an OAM in the Australia Day Honours in 2011 for services to medicine in the disciplines of oncology and pharmacology. He was also awarded the Eric Susman Prize from the Royal Australasian College of Physicians in 2013. In 2015 he was elected to the newly created Australian Academy of Health and Medical Science. He was also elected to be an inaugural member of Best Doctors in Australia and New Zealand in 2012.
Prof Clarke is Head of the NSW committee of the RACP and is Oncology Advisor to the Department of Veterans Affairs as well as a Member of the Repatriation Pharmaceutical Review Committee. He has received over $25 million in competitive research funding, which has produced over 260 publications, leading to more than 10000 citations.