The quarterly literature reviews provide an update to the comprehensive literature search previously conducted on behalf of the Department of Health. To ensure that the core messages of the Biosimilar Education Grant remain relevant and factual, the reviews examine all international and Australian clinical, academic and policy journals in relation to biosimilar medicines.
The reviews are conducted with an emphasis on ensuring that the evidence is up-to-date in the following key areas:
- Comparability of biosimilar medicines to reference biological medicines, specifically in reference to substitution (including single switch and multiple switch scenarios), and extrapolation of indication
- Biosimilar medicine uptake related to prescribing and dispensing trends, particularly evidence relating to policies on biosimilar medicine use
- Health outcomes and adverse events of biological and biosimilar medicines from a pharmacovigilance perspective
- Current perceptions of biosimilar medicines (qualitative and quantitative evidence) relating to awareness, confidence, attitudes and acceptance